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АuthorsT. Boletska

Pages: 153–160


The article shows the existence of a hidden epidemic process of Lyme borreliosis in Sumy region. It is evidenced by the presence of positive titers of IgG antibodies against B. burgdorferi in 70.5% of persons of risk group. Complaints along with positive titers of IgG antibodies against B. burgdorferi may be a sign of chronic latent course of Lyme borreliosis. In order to prevent complications it is important to examine these individuals. Identified hematological changes in the group of seropositive individuals indicate disturbances in the immune system, such as the prevalence of humoral component (increase of lymphocytic index, allergization index) and inhibition of cellular component of immunity (increasing of lymphocyte granulocyte index, decrease of neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio, neutrophil-monocyte ratio, neutrophils reactive response). These changes create favorable conditions for the development of autoimmune processes in the body. That’s why persons from risk group need constant clinical supervision.

Keywords: Lyme borreliosis, immune layer, hematological indices, immunity, risk group.

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  1. Sandugey AV, Hrustalev OA, Baranova NS. [Trudnosti klinicheskoy diagnostiki Laym-borrelioza]. Uchenyiezapiski Petrozavodskogo gosudarstvennogo universiteta. 2011; 8: 42–46.
  2. Skripchenko NV, Balinova AA. [Current knowledge of Lyme disease’s pathogenesis]. Zhurnal infektologii. 2012;2 (T. 4): 5–14.
  3. Batsyura AV. [Problema Laym-borrelioza v praktike klinitsista]. Klinicheskaya immunologiya. Allergologiya. Infektologiya. 2011; 4: 17 – 26.
  4. Baranova NS. Porazhenie nervnoy sistemy i pri hronicheskom Laym-borrelioze: avtoref. dis. nasoiskanieuchen. step. d-ramed. nauk: spets. 14.01.11 "Nervnyiebolezni". Moskva, 2013. 47 p.
  5. Rizzoli A, Silaghi C, Obiegala A. [Ixodesricinus and its transmitted pathogens in urban and peri-urban areas in Europe: New hazards and relevance for Public Health]. Front Public Health. 2014; 2: 251.
  6. Estrada-Peña A, Ayllón H, J. de la Fuente [Impact of climate trends on tick-borne pathogen transmission]. Frontiersin Physiology. 2012; 3(64). Retrieved from:
  7. Herrmann C, Gern L. [Search for blood or water is influenced by Borrelia burgdorferi in Ixodesricinus]. Parasit&Vectors. 2015; 8(1): 6.
  8. Lewandowska A, Kruba Z, FilipR. [Epidemiology of Lyme disease among workers of forest inspectorates in Poland]. Annals of Agricultural and Environmental Medicine. 2013;2(20): 329 - 331.
  9. Xian-Bo Wu, Ren-Hua Na, Shan-Shan Wei. [Distribution of tick-borne diseases in China]. Parasit&Vectors.2013;6:119. doi: 10.1186/1756-3305-6-119.
  10. Volkov VP. [Otsenka integralnyih leykotsitarnyih indeksov pri ih ispolzovanii v psihiatricheskoy praktike]. Sovremennaya meditsina: tendentsii razvitiya: materialy i Mezhdunarodnoy zaochnoy nauchno-prakticheskoy konferentsii. Novosibirsk, 2013. P. 104.