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APPLICATION OF DIGITAL HOLOGRAPHIC INTERFERENCE MICROSCOPY AND ELECTRON MICROSCOPY TO STUDY RATS’ ERYTHROCYTES OWING TO THE INFLUENCE OF HEAVY METAL SALTS

Authors: Tishko T.T., Tishko D.N., Titar V.P. , Prykhodko O.O., Bumeister V.I.

Pages: 22-29

Abstract

       

We employed the combination of the digital holographic interference and electron microscopy methods to study 3D morphology of rats’ blood erythrocytes o. The rats drank water with high concentration of heavy metal salts for a month. The results showed considerable morphological changes of blood erythrocytes in animals from experimental group: the number of transformed and degenerative erythrocytes increased, the average diameter of normal erythrocytes decreased and shape transformations of normal erythrocytes regarding sphericity coefficients increased.

Key wordsdigital holographic interference microscopy, electron microscopy, red blood cell morphology, 3D imaging, sphericity coefficient, heavy metal salt, rat.

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